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Benefits are cumulative with regular treatment

As these harmful factors damage the kidneys, the kidneys adapt in an effort to continue to meet the bodys needs for filtration

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These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19