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** The result depends on individual metabolism What's the variation within a milligram (mg), microgram (mcg), and an International Unit (IU)

"Some people are deficient and feel a lot better when given a shot, but just to pep you up, there's no study that says it's helpful." B12 is created by bacteria, including those living in the digestive tract

Muhlhausler BS, Belobrajdic D, Wymond B, Benassi-Evans B

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A further study presented at Digestive Disease Week 2025 of 993 patients found GLP-1RA to be associated with a statistically significant increase in clinical remission rates (HBI or Mayo score) at 3 months numerical at 6 and 12 months without an increase in side-effects