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CIP/KIP family cyclin-dependent kinase inhibitors are conserved targets of PUF proteins as they were found to be regulated by PUFs in mouse embryos and human cells (Kedde et al., 2010

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Rosenblum MD, Gratz IK, Paw JS, Abbas AK

doi: 10.2217/fmb.13.101 56 VallabhaneniS.ModyR

Skin Concerns Loss Of Radiance Dryness Loss Of Firmness Loss Of Volume Loss Of Elasticity Deep Wrinkles & Creases Texture: Oil Consistency: light weight Scent: Natural, aromatic rose Clinical Results 89% saw significant improvement in skin hydration for 24 hours* Significant improvement in skin barrier function for 24 hours* 89% saw significant improvement in skin radiance after 8 weeks* Significant improvement in skin brightness, firmness, elasticity, deep lines, wrinkles and expression lines after 8 weeks* *In a clinical study of 28 women