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Why? Fatigue is a frequent complaint for those on GLP-1 medications

Participants were assigned in a two-to-one ratio to receive either oral semaglutide 25 milligrams once daily or placebo, alongside standardized lifestyle interventions that included diet and physical activity counseling

Participants in this experiment complained of headache, fatigue, insomnia, intestinal disturbances, and numbness and tingling of their hands and feet (31)

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No published human RCTs examine IGF-1 LR3 specifically for body composition or fat loss in healthy adults