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Han J, Lee WJ, Hur KY, Cho JH, Lee BW, Park CY

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RBL monolayers (-2 X 10' cells) in 75-cm' flasks were rinsed twice with cold PBS and directly lysed in 4 ml of 4 M guanidium isothiocyanate solution

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The rising prevalence of diabetes and obesity globally is a major public health concern and necessitates early treatment

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In summary, it is noted that the interaction with the Glu205/206 pair and the S 1 pocket is crucial for inhibitory potency

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