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(No, you cant just start with the highest possible dose off the bat, since that may worsen its side effects, according to Kushner.) What to consider before going on a GLP-1 weight-loss medication As long as you meet the medical criteria, which is having a BMI above 30 or having a BMI of 27 as well as a weight-related health condition like high blood pressure, you can be a candidate for a GLP-1 like Wegovy

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