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Ann Neurol (1992) 32:33944 10.1002/ana.410320306 [DOI] [PubMed] [Google Scholar] 93.Chai SY, Mendelsohn FA, Paxinos G

This complacency comes just as we are reaching a critical mass of adoption, impacting consumer behavior at scale

Why this trial matters: First large Phase III evidence of biopsy-confirmed histologic benefit with a metabolic drug in MASH Demonstrates semaglutides impact beyond weight loss to disease-modifying liver effects Supports expanding GLP-1 therapeutics into liver disease care amid a high unmet need Ianalumab Meets Endpoints in Phase III Sjgrens Disease Trials (NEPTUNUS-1 & 2) Novartis reported that both Phase III studies of ianalumab achieved their primary endpoints in patients with Sjgrens disease, offering the first targeted therapy with statistically significant disease activity reduction in this chronic autoimmune disorder

It may be an enzyme called NNMT quietly throttling your fat cells' metabolism

The brain regions where BDNF exerts its strongest influence are the hippocampus, the prefrontal cortex, and the basal forebrain