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Given that SDH oxidizes succinate to fumarate while reducing CoQ 10 , one might predict that it functions similarly to other mitochondrial CoQ 10 oxidoreductases in suppressing ferroptosis by promoting ubiquinol (CoQ 10 H 2 ) production

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They later reported an increased prevalence of this deletion in male-male multiplex autism families, suggesting a potential link between TMLHE deficiency and autism risk 7

doi: 10.1089/108076802317373941, 102