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indeed, testosterone is known to positively influence libido and sexual behavior, and to enhance the activity of penile eNOS and nNOS enzymes, therefore stimulating cavernous smooth muscle relaxation and vasodilation of the cavernous arteries [2, 3]

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Kidney Int 62:15241538 Fliser D (2005) Asymmetric dimethylarginine (ADMA): the silent transition from an uraemic toxin to a global cardiovascular risk molecule

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The PVN receives major inputs from the amygdala, which plays a key role in the management of emotional stimuli (253, 274), and from the PBN in the brainstem, a hub nucleus for the detection of inflammatory stimuli (252)