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480 However, the precise mechanisms through which these molecules and pathways contribute to ferroptosis, as well as the ways in which ferroptosis exacerbates hypertrophic growth of cardiomyocytes, remain poorly understood and warrant further investigation

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Cells were resuspended in 200 l staining buffer and analyzed within the hour using a CytoFLEX S flow cytometer (Beckman Coulter)

No clinical trial has tested the exact combination, but the closely related CagriSema (cagrilintide + semaglutide) Phase 3 trial showed that adding amylin to a GLP-1 backbone improves weight loss