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The unknown rate constants for R 1 , R 2 , R 3 , R 4 and R 5 for the respective models were fitted using the LSQNONLIN function in MATLAB, a non-linear least squares solver

Notably, our results on GABA align with several prior studies using optimized sequences such as MEGA-PRESS [25], suggesting that methodological sensitivity is unlikely to be the sole factor responsible for the non-significant findings

In this process, free radicals steal electrons from lipids in the cell membrane, thereby leading to cell damage