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According to the gut-thyroid axis in HT, the pathogenesis of CD and NCWS can be explained from the following aspects: shared cytokine, molecular simulation, abnormal post-translational modification of proteins, malabsorption of essential micronutrients for the thyroid and damaged intestinal barrier [25]

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During fasting, this is of special importance as most tissues other than the brain can thereby utilize fatty acids directly to generate energy

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