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Due to accumulation of metabolic intermediates, impaired carnitine biosynthesis, reduced protein intake, and increased removal of carnitine through hemodialysis (HD), patients who undergo routine HD usually present with plasma carnitine insufficiency [54]

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There is no specific Zepbound or Mounjaro diet, but in clinical trials, people on tirzepatide lost weight by eating balanced meals and maintaining a 500-calorie deficit a day

This approach allowed us to account for variability between experiments while preserving relative differences between ECM conditions