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Figure 2 Exenatide, a peptide of 39 amino acids, has a much slower metabolism than endogenous GLP-1 (half-life of 3-4 h) (119, 120)

Hippocampus 33(4):307321 Colin IM et al (2023) Emerging evidence for the use of antidiabetic drugs, glucagon-like peptide 1 receptor agonists, for the treatment of Alzheimers disease

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At 3 years, the semaglutide group had an 8.9% cumulative incidence of NAION compared with a 1.8% incidence for the comparator group