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Peripheral infusion of GLP-1 decreases food consumption and increases satiety in both normal and obese individuals, presumably by interaction with sensory neurones in the gastrointestinal tract or hepatoportal region (Trapp and Brierley 2022)
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The article on semaglutide withdrawal symptoms explains what to expect and how to manage the transition
Strategies to Prevent Weight Regain GLP-1s Are a ToolNot a Shortcut FAQs The science This is a really important subject and there are lots of people studying this
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