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Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRAS(G12C), are associated with renal toxicity in the Sprague Dawley rat

These individuals may require closer monitoring and more aggressive preventive strategies

Iron overload, resulting from dysregulated iron metabolism, is a well-established initiating factor for ferroptosis (Yang et al., 2018)

however, because of the potential for serious adverse effects in the nursing infants, breastfeeding while taking phentermine is not recommended

Long-term prophylaxis with Lanadelumab led to a significant reduction in attack frequency and severity, improving his quality of life (Figure 1 shows the QoL questionnaire results)