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Indeed, a decrease in the carnitine-dependent fatty acid transport system causes an accumulation of acyl-CoA molecules in the cytosol, and these metabolites inhibit the urea cycle ( Malaguarnera, 2013 )

N-3 PUFAs were only partially inhibiting this increase, potentially because N-3 PUFA supplementation could lead to exaggerated sensitivity to lipid peroxidation [201]

Rogawski MA (2016) A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors

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He is the author of Medicare Mastery Unlocked: Your Roadmap to Maximizing Benefits and Minimizing Confusion (2025)