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It's important to understand that these medications follow a gradual dose escalation schedule to minimize side effects, particularly nausea and gastrointestinal discomfort

Team-based care, including registered dietitian nutritionists (RDNs), exercise physiologists, and health coaches, can be very helpful, but these are not always available depending on health system circumstances and payer policies

Berg S et al

A critical real-world evidence (RWE) appraisal of these cohorts reveals significant limitations