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But copper is also one of those minerals that people can have too much of, or handle poorly, especially if other parts of the mineral system are off

This methodological heterogeneity complicates both interstudy comparisons and the development of clinical guidelines

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78,80,81,82 Approximately 10% of them are copy number variations (CNVs) that disrupt protein coding, including chromosomal duplications, large deletions, inversions, and translocations, such as 1q21.1 duplications or deletions, 3q29 deletions, 7q11.23 duplications, 15q11-q13 deletions, 15q13.3 microdeletions, 15q11-13 duplications, 17q12 deletions, 22q11.2 deletions and 22q13.33 duplications or deletions