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doi: 10.1080/15548627.2015.1100930 16 SaylorAJMcGintyJF

two months) significantly reduces glial activation in the brain and ameliorates the synthesis of NO, iNOS, TNF-, as well as IL1- (104)

Bloomer RJ, Solis AD, Fisher-Wellman KH, Smith WA: Postprandial oxidative stress is exacerbated in cigarette smokers

Mechanistically, BL-mediated protection involves downregulation of IFN- production, attenuation of cytotoxic microglial activation and CD4 + T cell responses, expansion of Treg populations, and suppression of Th17 cell differentiation

Appetite and craving control tend to build over two to three weeks of consistent use