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2.1 The clinical signs The clinical signs of primary diffuse meningeal melanomatosis are very diverse: meningeal symptoms, mental disorders, and focal lesions of the cranial and spinal nerves, accompanied by peripheral paralysis and areflexia

In a severely degenerated disc, administration of bioactive molecules may have a limited response secondary to a low healthy cell density

14 cystine withdrawal, thus demonstrating the importance of cysteine de novo synthesis for melanoma biology [70]