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These may include issues related to intestinal permeability, irritation, or imbalance within the gut environment

Chronic gut permeability is where it becomes a problem LPS crossing into the bloodstream can get past the blood-brain barrier too When it does, it activates microglia (the brains immune cells) which start breaking down the blood-brain barrier

TB-500, in contrast, functions through actin sequestration, promoting cell migration and reducing inflammation via distinct cytokine pathways