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( ad ) Representative dose-response curves of cAMP assays in cells expressing human GIPR (A), human GLP-1R (B), mouse GIPR (C), or mouse GLP-1R (D)

Oral administration of danuglipron to healthy humans produced dose-proportional increases in systemic exposure (NCT03309241)

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But in practice, these are fundamentally different compounds with different receptor profiles, different side effect landscapes, and different outcomes for the people who use them