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Conclusion Metformin and GLP-1 medications each support weight loss through unique pathwaysbut when used together, they may deliver enhanced and sustainable results

When combined with strength, nutrition, and long-term lifestyle changes, GLP-1 therapy can support healthier arteries, a more resilient heart, and lower cardiovascular risk over time

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The 2025 decision to raise NICEs range to 25k35k ( [4] ) suggests UK policy is moving toward greater emphasis on supporting innovation (at least for now) and alleviating business climate concerns