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Clinics prescribe 1ml weekly because it's the middle-ground safe dose, not because it's optimised for your liver's methylation capacity, your dietary methionine intake, or your current rate of fat oxidation

A meta-analysis found that people taking GLP-1 RAs (including semaglutide) lose an average of 11% of their starting weight

Hypoxia increases cell adhesion, coagulant properties, endothelial intracellular gaps, and endothelial permeability, all of which are crucial for the processes of intravasation, and extravasation needed for cancer cell metastasis (Evans et al., 2012)

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Dehydration will worsen constipation and other digestive discomforts