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Como principales indicadores de xito del tratamiento antioxidante, se consideraron la mejora en el ndice de vacuolizacin y en la fragmentacin del ADN espermtico

10.1016/j.metabol.2013.09.005 264 PickkersP.GarchaR

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In our study, we found that the increased A plaques firstly appeared in the cortex and hippocampus of earlier 8-week ethanol exposed APP/PS1 mice (in both 2BC and IP paradigms), and no A plaque was found even after 10 weeks ethanol exposure in WT mice, suggesting that chronic ethanol exposure did not directly result in A plaques but accelerate the A deposition

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