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FDA's Category 2 designation closed that gap
Efficacy unclear
Inflammation plays a critical role in cancer cachexia, and BPC157 effectively suppressed the expressions of TNF- and IL-6, both of which are pro-inflammatory cytokines implicated in cachexia
In animal studies, very high doses of sermorelin (several times the human dose) produced minor variations in fetal development in rats and rabbits
Contemporary trial data in high risk patient groups do not show convincing evidence that intensive lipid lowering causes major neurocognitive harm, dementia, or a clear excess of haemorrhagic stroke in selected patients, even at very low achieved LDL-C levels [9], [10], [11], [12], [13], [14], [15], [16]
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