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Extended abstinence periods between ejaculations naturally increase semen volume, as do reproductive tract infections and certain hormonal imbalances affecting the prostate and seminal vesicles

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Elevated cortisol also lowers TSH, reducing the production of T4 and T3

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These teams and their collective wisdom will ensure progress in irAE diagnosis and management, guided by insights from both clinical care and biospecimens obtained at key timepoints, such as baseline, time of irAE diagnosis and irAE resolution