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Harvard Health Publishing says, a severe vitamin B12 deficiency can lead to deep depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell, and more

This helps determine whether theres an imbalance in the gut or not

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There might also be opportunities for GLP-1 drugs to be modified somehow to circumvent the impacts of these PAM gene variations but it's still early days in that regard

DOI: 10.1016/s0033-0620(97)80037-0 Eder, K., Felgner, J., Becker, K., & Kluge, H