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Juszczak F, et al

Clinical studies suggest that GLP-1 analogs can mitigate symptoms in patients with Crohns Disease and Ulcerative Colitis by reducing macrophage activation and restoring epithelial integrity (Cani et al., 2016)

For example, exendin-4 has been shown to potentiate the antiproliferative effects of ionizing radiation and increase radiation-induced G2/M phase arrest, whereas liraglutide enhances the effects of docetaxel in prostate cancer cells

These limited reports suggest good tolerability, though the small sample sizes, lack of standardized safety monitoring, and retrospective or uncontrolled study designs limit definitive safety conclusions

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