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The decision to continue or discontinue semaglutide treatments should be made after consulting with your medical provider and depends on several factors, including your overall health and if youre experiencing more severe side effects

3 However, gastrointestinal side effects increased with high dosage

The observed metabolic-research differences between the two compounds are therefore not explainable by tirzepatide hits GLP-1 harder. They are explainable by the synergistic effect of dual-receptor engagement, where GIPR activation amplifies the downstream consequence of a lower-affinity GLP-1R hit

[1] Where to inject semaglutide You take a weekly dose of semaglutide via subcutaneous injection, which means you inject it into the fatty tissue just under your skin

There is limited data on the effects of Ozempic use during pregnancy in humans, and the available data is conflicting