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Results at 72 weeks were striking: 5mg dose: 15.0% average weight loss 10mg dose: 19.5% average weight loss 15mg dose: 20.9% average weight loss Placebo: 3.1% average weight loss At the highest dose, 36.2% of participants lost 25% or more of their body weight

Patients with these conditions require careful evaluation by their provider before initiating therapy, as they may be at increased the risk for gastrointestinal adverse effects or complications

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DunedinPACE, a DNA methylation biomarker of the pace of aging