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The negative moderating effect of the total intervention period (weeks) suggests that indefinite extension of the intervention may lead to diminishing returns

This type of compound undergoes GST-catalyzed breakdown to release locally cytotoxic metabolites and thereby attenuate off target adverse side effects

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Typically prescribed for patients with laboratory-confirmed B12 deficiency, pernicious anemia, or nerve-related symptoms linked to low B12 especially when oral supplementation has failed or absorption is impaired (e.g

doi: 10.1007/s13197-020-04360-2, 30