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Classifying recommendations for clinical practice guidelines

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& Wahl, S

These symptoms do not tend to improve spontaneously throughout the progression of the disease and about one-third of patients demonstrate a poor response to the antipsychotics commonly used today, such as Chlorpromazine (8,9)

Nevertheless, transcriptional modifications may also lead to delays in recovery, as ongoing perturbations on a transcriptional level were observed for up to 6 months after infection, with PASC patients showing a distinct profile, such as upregulation of the alarmins S100A8 and HMGB1, mediators and markers of innate immune activation (124)