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1,5 Your GP will adjust your prescription based on your TSH

Davies M, Frch L, Jeppesen OK, Pakseresht A, Pedersen SD, Perreault L, Rosenstock J, Shimomura I, Viljoen A, Wadden TA, Lingvay I, STEP 2 Study Group (2021) Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

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Gastroenterology 149 , 389397.e310 (2015)

At this years ADA, results from the REWIND trial showed that Trulicity, a once-weekly injectable GLP-1, resulted in a 12% reduced risk of combined non-fatal stroke, non-fatal heart attack, and heart-related death compared to placebo (a nothing pill)