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These radicals react about 1,000 times faster with -tocopherol (vitamin E) than with unsaturated lipids

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Chronic supplementation with a mitochondrial antioxidant (MitoQ) improves vascular function in healthy older adults

Furthermore, disruption of cholesterol homeostasis and lipid raft integrity directly interferes with membrane-associated signal transduction, leading to hyperactivation of pro-inflammatory signaling cascades and impaired communication among immune cells, ultimately fostering an immunosuppressive microenvironment