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While administration of antibiotics decreases adult neurogenesis (Mohle et al., 2016), the indole-AHR signaling pathway highlights microbiota as a direct modulator to hippocampal neurogenesis

Because IGF-I exerts anti-inflammatory actions and is important for peripheral glucose uptake, metabolic disturbances in these patients can, in part, be explained by the low IGF-I levels (83)

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