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Signs to watch for include hives, difficulty breathing, swelling of the face or throat, and rapid heartbeat
Effect of propionyl-l-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease
Moreover, depression is characterized by high prevalence of coexistence with many metabolic diseases, such as type 2 diabetes mellitus (T2DM) and obesity, and brain insulin resistance observed in both of these diseases is currently considered an important factor which may lead to the manifestation of depressive symptoms [10, 11]
However, adverse effects may limit the treatment potential, e.g., glitazones are associated with phenotypical weight gain [136] and obeticholic acid induced pruritus and elevated LDL-C [137], the latter a potential concern in patients already at risk for cardiovascular disease
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