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In a study by Li et al

It was identified as an activity that markedly stimulated CO2 production and lipid synthesis in liver slices and stimulated protein, RNA, and DNA production in neoplastic and normal liver cell culture

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Additionally, its stress reducing properties, through stabilizing the hypothalamic-pituitary-adrenal (HPA) axis and lowering cortisol levels, help reduce inflammation and tension that can exacerbate pain

Results: Meta-analysis showed a statistically significant effect of curcumin on depressive symptoms (SMD: 0.65, P = 0.01, 95% CI: 1.16 to 0.13, I 2 = 93%) and anxiety symptoms (SMD: 0.22, P = 0.01, 95% CI: 0.40 to 0.05, I 2 = 0%)