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Adv Healthcare Mater, 2022, 11: 2101926 Acknowledgements This work was supported by the National Natural Science Foundation of China (62175262), the Science and Technology Innovation Program of Hunan Province (2022RC1201), the Fundamental Research Fund for the Central South Universities (2020CX021), the Key R & D plan of Hunan Province (2022SK2101), and the Scientific Research Launch Project for new employees of the Second Xiangya Hospital of Central South University

(2018) indicate that the administration of the selective peptide inhibitor P110 to SOD1-G93A model mice resulted in the inhibition of Drp1/Fis1 expression, which in turn led to a reduction in mitochondrial structural defects in motor neurons, an improvement in motor function and a reduction in muscle atrophy, and an increase in the survival rate of the model mice

Quality pharmaceuticals: We use pharmaceutical-grade vitamin C specifically manufactured for intravenous use, not reconstituted supplements

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By targeting key signaling pathways, including AR signaling, p53 networks, PTEN/PI3K/AKT, and Wnt/-catenin cascades, miRNAs modulate cancer stemness, cell cycle progression, apoptotic resistance, and metastatic competence