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Moreover, metallic NPs (particularly silver and gold) are often associated with antimicrobial activity, which may raise concerns about promoting microbial resistance or biofilm-associated tolerance [149]

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In laboratory studies, KPV reduces activation of NFB and MAPK pathways, which are central to inflammatory responses

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Of note, SARS-CoV-2 and RSV were also sensitive towards inhibition when the compounds were given after infection, indicating that in addition to the effects on entry, metabolism is also relevant for the observed antiviral activity