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5 *Events are listed according to system organ class

Data were analysed using one-way ANOVA with Bonferroni post hoc multiple-comparison test ( b , f , h ) two-way repeated-measures ANOVA ( a , c , d , e , g ), Kruskall-Wallis test with uncorrected Dunnss test ( i ), or Analysis of Covariance (ANCOVA) with body weight as covariate ( j )

Many individuals experience more consistent weight-loss progress during the third to sixth month of therapy

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