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Short-chain fatty acids can then stimulate GLP-1

Overweight: BMI of 27 or higher with at least one weight-related health condition, like type 2 diabetes, high blood pressure, or high cholesterol

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Berberine may modestly reduce total cholesterol, LDL cholesterol, and triglycerides in some studies, whilst L-carnitine has been examined in the context of cardiovascular health

GLP-1 drugs and the broader Make America Healthy Again mood vilifying sugar, dyes and ultra-processed fare, have pushed culture from body-positivity to body-optimization