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These include mitogen-activated protein kinase and nuclear factor-B (NF-B), which lead to the expression of inflammatory cytokines, chemokines, and adhesion molecules

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The inclusion of Alpha Lipoic Acid, Collagen Extract, and Epidermal Growth Factor further enhances the formula, making it a powerhouse of skin rejuvenation

AMPK is the main energy sensor that regulates the dynamic balance of ATP/AMP levels up-regulated and phosphorylated by APS (Zou et al., 2009