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Like any medication, GLP-1 agonists have side effects

The user group had lower risk of major adverse cardiovascular events (MACE) (HR 0.88), as well as a lower risk of major adverse kidney events (MAKE) (HR 0.73)

Because these medications trigger insulin production, slow the emptying of the stomach and cause you to feel full faster and for longer periods of time, eating unhealthy foods or larger portions of food may cause negative gastrointestinal side effects, including abdominal pain, nausea or vomiting, Ngo-Hamilton says

This method strikes a balance by reducing the impact of large-fold changes while preserving the inherent variability of the data