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7 Compared to other antidiabetic drugs, GLP-1 RAs have the advantage of only being pharmacologically active when blood glucose levels are high

[DOI] [PubMed] [Google Scholar] 208.Argyrakopoulou G., Konstantinidou S.K., Dalamaga M., Kokkinos A

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on the other hand, the comparison with insulin degludec showed that although insulin, titrated during the study, obtained a better result on fasting blood glucose, treatment with tirzepatide 10 and 15 mg demonstrated better control on all other points of glucose profile [60]

DSIP stimulates the release of LH, suggesting that it might also activate the responsible hypothalamic neural circuit