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Catalytic metal sites are structurally diverse and encompass a remarkable breadth of catalytic power, as members of all seven major classes of enzymes as categorized by the Enzyme Commission (EC): oxidoreductases (EC 1), transferases (EC 2), hydrolases (EC 3), lyases (EC 4), isomerases (EC 5), ligases (EC 6), and translocases (EC 7)

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Female Balb/c mice (8 weeks, Animal Resources Centre, Perth, WA, Australia) were housed at 20 2C and maintained on a 12 h light, 12 h dark cycle (lights on at 06:00 h) with ad libitum access to standard rodent chow and water

The somatic genomic landscape of glioblastoma