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Three key signalling molecules in the Wnt/-catenin signalling pathwayWnt3a, -catenin, and Cyclin D1are upregulated at the mRNA and protein levels in the adult spinal cord of SOD1 (G93A) ALS transgenic mice and are related to gliosis of the adult spinal cord in ALS transgenic mice

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Male Sprague-Dawley rats (Janvier) were regularly introduced in the breading to maintain the colony of heterozygous animals