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These factors activate hepatic stellate cells and fibroblasts to produce extracellular matrix proteins involved in collagen synthesis, with Col1a1 as one major player (2729)

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In a diet-induced rat model of MASH, genistein supplementation reduced multiple markers of severity of liver inflammation including hepatic TNF- level, inflammatory cell inflammation, and overall histological severity (161)

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Pll, D., Katona, E., Juhsz, M