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If the answer to any of these questions is yes, inform your provider before the next scheduled dose increase

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We asked whether the higher expression of proteins associated with DNA repair in young-adult individuals was entirely explained by proliferation-dependent DNA damage

For this reason, drugs with a long half-life (e.g., amiodarone, elimination t 1/2 of about 58 days) are usually started with a loading dose to achieve their desired clinical effect more quickly